Bona Fide Optical Discs and Players for Molecular Diagnostics

主讲人 :于化忠 加拿大西蒙弗雷泽大学化学系教授

Current guidelines for healthcare emphasize rapid testing and reporting, which can be better satisfied by point-of-care (POC) diagnostic tools rather than centralized medical laboratories using automated multi-analyte analyzers by trained professionals. With POC testing, the turn-around time is significantly reduced, leading to earlier decision making and more efficient medical treatment. At present, POC protocols are predominantly d on rapid-test immunoassay strips/cassettes that combine gold nanoparticles for colorimetric (mostly qualitative) detection and flow-through systems for sample delivery. Optical disc technology provides a promising alternative to today’s POC testing protocol; we have established both the surface chemistry and signal reading methodology for running bioassays of various molecular analytes on bona fide optical discs (CD, DVD, and Blu-ray discs); these bioDiscs can be read quantitatively with standard computer drives or stand-alone disc p s, i.e., without any modifications to the hardware and software driver.

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主讲人简介：

于化忠，现任加拿大温哥华市西蒙弗雷泽大学（Simon Fraser University：SFU）化学系教授，同时兼任4D先进材料实验中心专任研究员和分子生物学及生物化学系教授。于教授1991年毕业于山东大学化学系；1994年获山东大学和中科院大连化物所联合培养硕士学位； 1997年获北京大学理学博士学位（刘忠范院士的首届博士生；北京大学优秀博士论文世顺奖）。同年赴美国加州理工学院(Caltech)开展博士后工作，师从诺贝尔奖获得者激光化学家兹维尔教授(Ahmed Zewail)和著名电化学家安森教授(Fred Anson)。2000年工作于加拿大国家科学院；2001年受聘于SFU，在2005 和2009年分别破格晋升为副教授和教授（生物分析化学和材料化学）。先后获加拿大化学会Fred Beamish 奖(2004)，电化学会加拿大分会W. Lash Miller 奖 (2011)，国际电化学学会Tajima 奖(2012)，以及最近的加拿大化学会W.A.E.McBryde 奖章。于教授发表论文120余篇，多数刊登在美国化学会(ACS)的核心期刊上。