姓 名：朱政霖
2000年9月-2004年7月，
南京航空航天大学生物医学工程专业（本科）。
2005年9月-2010年7月，
北京大学生命科学学院生物学专业（博士）。
2010年7月-今，
重庆大学生命科学学院，副教授。
合作伙伴
中国科学院动物研究所遗传学实验室张勇博士。
中国农业大学动物医学院孟赓博士。
项目
获得国家自然科学基金2项，校级基金3项. 参与国家级重大课题1项，其它国家级课题4项。 |
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研究方向
1、生物信息学算法及软件
2、遗传及进化
3、动植物疾病
学术兼职
杂志审稿人：Molecular Biology Evolution, Scientific Reports, Database (Oxford), Biocatalysis and Agricultural Biotechnology, Biomedical and Environmental Sciences, Hereditas, Infection and Drug Resistance, Journal of Pediatric Infectious Diseases, International Journal of Virology & Infectious Diseases, Journal of Vaccines and Immunology, Annals of Public Health Reports, Research and Reviews of Infectious Diseases, American Journal of Epidemiology & Public Health
重庆市生物信息学会常务理事，国家自然科学基金评审，重庆市自然科学基金评审。
主讲课程
《生物信息学》、《Perl编程》和《群体遗传学》
发表论文
Tan M#, Xia J#, Luo H#, Meng G*, Zhu Z* Applying the digital data and the bioinformatics tools in SARS-CoV-2 research. Computational and Structural Biotechnology Journal (2023) 21, 4697-4705
CSBJ2023.pdf
Zhu ZM, Xiong Z, Zou W, Shi Z, Li S, Zhang X, Liu S, Liu Y, Luo X, Ren J, Zhu Z*, Dong P* Anti-oomycete ability of scopolamine against Phytophthora infestans, a terrible pathogen of potato late blight. J Sci Food Agric (2023) 10.1002/jsfa.12717JSFA2023.pdf
Lin X#, Sha Z#, Trimpert J, Kunec D, Jiang C, Xiong Y, Xu B, Zhu Z*, Xue W*, Wu H* The NSP4 T492I mutation increases SARS-CoV-2infectivity by altering non-structural protein cleavage. Cell Host & Microbe (2023) 12(31), 1170-1184CellMH2023.pdf
Shi Z, Zou W, Zhu ZM, Xiong Z, Li S, Dong P*, Zhu Z* Tropane alkaloids (hyoscyamine, scopolamine and atropine) from genus Datura: extractions, contents, syntheses and effects. Ind Crop Prod (2022) 186, 115283ICP2022.pdf
Feng S, Tang S, Jian Y, Huang X, Jin L, Zhu Z, Dong P*, Li Z* Complete Genome Sequence Data of a Novel Streptomyces sp. Strain A2-16, a Potential Biological Control Agent for Potato Late Blight. Plant Dis (2022) 106(2), 723-726PD2022.pdf
Wu H#, Xing N#, Meng K#, Fu B#, Xue W, Dong P, Tang W, Xiao Y, Liu G, Luo H, Zhu W, Lin X*, Meng G*, Zhu Z* Nucleocapsid mutations R203K/G204R increase the infectivity, fitness, and virulence of SARS-CoV-2. Cell Host & Microbe (2021) 29, 1788-1801CellHM2021.pdf
Zhu Z*#, Tan Y#, Xiao S#, Guan Z#, Zhao W, Dai Z, Liu G, Zhang Z* Solitary Living Brings a DecreasedWeight and an Increased Agility to the Domestic Silkworm, Bombyx mori. Insects (2021) 12, 809Insects2021.pdf
Zhu Z*, Liu G, Meng K, Yang L, Liu D, Meng G*, Rapid Spread of Mutant Alleles in Worldwide SARS-CoV-2 Strains Revealed by Genome-Wide Single Nucleotide Polymorphism and Variation Analysis. Genome Biology and Evolution (2021) 13, 2gbe-2021.pdf
Fu Y, Zhu Z, Meng G, Zhang R*, Zhang Y*. A CRISPR-Cas9 based shuffle system for endogenous histone H3 and H4 combinatorial mutagenesis. Sci Rep. (2021) 11(1):3298.sr_2021_yeast.pdf
Zhu Z*, Meng K, Liu G, Meng G*. A database resource and online analysis tools for coronaviruses on a historical and global scale. Database (Oxford) (2020) baaa070. doi: 10.1093/database/baaa070.db-2020.pdf
Zhu Z* , Wang Y, Zhou X, Yang L, Meng G*, Zhang Z. SWAV: a web-based visualization browser for sliding window analysis. Sci Rep (2020) 10, 149.swav.pdf
Zhu Z* , Meng G*. ASFVdb: An integrative resource for genomics and proteomics analyses of African swine fever. Database (Oxford) (2020) baaa023. doi: 10.1093/database/baaa023.asfvdb.pdf
Zhu Z*, Meng K, Meng G*. Genomic recombination events may reveal the evolution of coronavirus and the origin of SARS-CoV-2. , Scientific Reports, 2020, 10(1): 0-21617.SR2020.pdf
Zhu Z* , Guan Z, Liu G, Wang Y, Zhang Z*. SGID: a comprehensive and interactive database of the silkworm. Database (Oxford). (2019) Jan 1;2019. pii: baz134.sgid.pdf
Shao Y, Chen C, Shen H, He BZ, Yu D, Jiang S, Zhao S, Gao Z, Zhu Z, Chen X, Fu Y, Chen H, Gao G, Long M, Zhang YE*. GenTree, an integrated resource for analyzing the evolution and function of primate-specific coding genes. Genome Res (2019); 29, 682-696.gentree.pdf
Zhu Z*, Tan S, Zhang Y, & Zhang YE*. LINE-1-like retrotransposons contribute to RNA-based gene duplication in dicots. Sci Rep (2016) 6, 24755.line1_retrogene.pdf
Tan S#, Zhu Z#, Zhu T#, Te R, Zhang YE* Chance and Necessity: Emerging Introns in Intronless Retrogenes. eLS (2014) doi:10.1002/9780470015902.a0022886,chance_and_neccesary.pdf
Zhao Q, Zhu Z, Kasahara M, Morishita S, Z Zhang*. Segmental duplications in the silkworm genome. BMC Genomics (2013)14:521bmori_segmental.pdf
Zhou X*, Li Q, Zhu Z, Zhao H, Tang H, Y Feng. Monitoring Epidemic Alert Levels by Analyzing Internet Search Volume. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING (2012) 99:1moniter_isv.pdf
Kang LF, Zhu Z*, Zhao Q, Chen LY*, Z Zhang. Newly evolved introns in human retrogenes provide novel insights into their evolutionary roles. BMC Evolutionary Biology (2012) 12:128human_retrogene.pdf
Zhu Z, Y Zhang, MY Long*. Extensive Structural Renovation of Retrogenes in the Evolution of the Populus Genome. Plant Physiol (2009) 151:1943–1951.plant_retro_intron.pdf
